Alchemical Concoctions

Alchemical Concoctions are non-magical consumables that have intended effects and, often, unintended side-effects. In magically restrictive societies, these are used to combat injuries, illness, and increase performance.

Concoction	Category	Properties	Type	Weight	Cost
Ash and Salt Gargle	Medicine		Ingest	1 lb	5 GP
Black Sulfur Salve	Medicine		Contact	1 lb	50 GP
Bloodletting Draught	Nostrum		Ingest	1 lb	400 GP
Blue Vitriol Draught	Medicine	Toxic	Ingest	1 lb	100 GP
Boiled Moss Poultice	Medicine		Contact	1 lb	25 GP
Burned Alum Mixture	Medicine		Contact	1 lb	50 GP
Burned Bone Infusion	Tonic		Ingest	1 lb	50 GP
Copper Draught	Poison	Toxic	Ingest	1 lb	300 GP
Dried Mandrake Powder	Anodyne	Addictive	Ingest	1 lb	100 GP
Malachite Powder	Nostrum	Toxic	Ingest	1 lb	5 GP
Oil of Vitriol	Poison		Contact	1 lb	300 GP
Opium Draught	Anodyne	Addictive	Ingest	1 lb	100 GP
Powdered Bloodstone	Nostrum		Ingest	1 lb	5 GP
Raw Honey Compress	Medicine		Contact	1 lb	25 GP
Saltpeter Tonic	Medicine		Ingest	1 lb	15 GP
Sanguine Tincture	Tonic		Ingest	1 lb	50 GP
Spirit of Hartshorn	Tonic		Inhale	1 lb	25 GP
Tincture of Quicksilver	Tonic	Toxic	Ingest	1 lb	50 GP
Verdigris Salve	Medicine	Toxic	Ingest	1 lb	50 GP
Vinegar of Four Thieves	Nostrum		Ingest	1 lb	250 GP

Properties

Addiction

Each time a creature uses this concoction, they must make a DC 15 Constitution saving throw. After two failed saves, they gain the Addicted condition. After 30 days without a dose, accumulated failed saves reset to zero. An Addicted creature continuously experiences this concoction's crash effects until they take another dose, after which the crash effects are suppressed for the duration of the concoction's normal effects. Once Addicted, for each Long Rest without a dose, the creature must repeat the Constitution saving throw or gain 1 level of Exhaustion. After 7 consecutive Long Rests without a dose, the Addicted condition ends and any Exhaustion gained this way is removed.

Toxic

Each time a creature uses this concoction, they must make a DC 10 Constitution saving throw. On a failure, their Constitution score is permanently reduced by 1. This reduction can only be reversed by a Greater Restoration spell or equivalent. A creature whose Constitution score reaches 0 this way dies.

Types

Medicine. A preparation that treats a condition or symptom through direct therapeutic action.
Poison. A preparation intended to cause harm.
Anodyne. A preparation that relieves pain.
Nostrum. A preparation of unproven or false efficacy, typically sold as a cure-all.
Tonic. A preparation that augments or enhances the body's performance.

Ash and Salt Gargle (5 GP)

As a Bonus Action, you can drink a vial of Ash and Salt Gargle to gain Advantage on saving throws against inhaled poisons for 10 minutes.

Diseases. Suppresses Cough and Coughing Blood for duration.

Black Sulfur Salve (50 GP)

As a Utilize Action, you can administer the Black Sulfur Salve to yourself or another willing creature within 5 feet of yourself. The creature regains 1d6 points of lost Hit Point maximum caused by necrotic effects. This salve does not restore Hit Points, only hit point maximum loss.

Bloodletting Draught (400 GP)

A creature subjected to Bloodletting Draught makes a DC 16 Constitution save when ingested or has the Poisoned condition for 1 hour. The creature also has Vulnerability to Piercing and Slashing damage and Disadvantage on Strength checks while Poisoned in this way. Often sold as a "purifying" tonic that supposedly balances bodily humors.

Blue Vitriol Draught (100 GP)

As a Bonus Action, you can drink a vial of Blue Vitriol Draught to end the effects of one ingested poison or toxin currently affecting you. You then have the Poisoned condition for 1 hour as your body expels the substance.

Diseases. Grants Advantage on Constitution saving throws against contracting diseases spread through contaminated food or water. Must be taken within 1 hour of exposure.

Boiled Moss Poultice (25 GP)

As a Utilize Action, you can administer the Boiled Moss Poultice to yourself or another willing creature within 5 feet of yourself. The next healing that creature receives within 10 minutes is maximized.

Diseases. Suppresses healing prevention for next healing received within the duration.

Burned Alum Mixture (50 GP)

As a Utilize Action, you can administer the Burned Alum Mixture to yourself or another willing creature within 5 feet of yourself. The creature regains 2d6 Hit Points, but must make a Constitution saving throw equal to 8 + Hit Points regained or become Incapacitated due to pain until the end of their next turn.

Diseases. Suppresses Bleeding and Blood loss for 1 hour.

Burned Bone Infusion (50 GP)

As a Bonus Action, you can drink a vial of Burned Bone Infusion to gain Advantage on Strength checks for 1 hour.

Diseases. Suppresses Weakness for duration.

Copper Draught (300 GP)

A creature subjected to Copper Draught makes a DC 15 Constitution save when ingested or has the Poisoned condition for 1 hour. The creature also cannot take Actions or Bonus Actions while Poisoned in this way.

Dried Mandrake Powder (100 GP)

This anodyne is a hallucinogen, sedative, and painkiller. Used in prophecy, ritual magic, and crude anesthesia, it distorts reality while dulling pain and leaving the user detached from the waking world.

For 6 hours, the user gains Advantage on Charisma (Performance) and Wisdom (Insight) checks and may choose to have Advantage on any one d20 Test during this time. They also gain Resistance to non-magical Bludgeoning, Piercing, and Slashing damage. However, they suffer Disadvantage on Perception (Sight) and Intelligence (Investigation) checks, as well as Initiative rolls.

Diseases. Suppresses Pain, Severe Headaches, Restless Sleep for duration.

After the effects wear off, the user experiences a crash for 2 hours, suffering Disadvantage on all Intelligence and Wisdom checks. Taking another dose alleviates these effects.

Malachite Powder (5 GP)

As a Bonus Action, you can drink a vial of Malachite Powder, but it has no discernible effect.

Oil of Vitriol (300 GP)

The target must make a DC 14 Dexterity saving throw. On a failure, they take 5d6 Acid damage and are Blinded for 1 minute. If mishandled, the user must make a DC 14 Dexterity saving throw or take 2d6 Acid damage. Used industrially but sometimes sold as a wart and infection remover.

Opium Draught (100 GP)

This anodyne is a euphoric, sedative, and painkiller. When ingested, it suppresses fear, dulls pain, and slows the body's responses.

For 6 hours, the user gains Advantage on saving throws against Fear, inhaled toxins, and Death. However, they also suffer Disadvantage on Intelligence (Knowledge) checks, Initiative rolls, and saving throws against the Unconscious condition.

Diseases. Suppresses Pain, Severe Headaches, Restless Sleep, Nausea, and Vomiting for duration.

After the effects wear off, the user experiences a crash for 2 hours, suffering Disadvantage on Strength and Dexterity checks and saving throws, as well as Intelligence (Knowledge) checks. Taking another dose alleviates these effects.

Powdered Bloodstone (5 GP)

As a Bonus Action, you can drink a vial of Powdered Bloodstone, but it has no discernable effect.

Raw Honey Compress (25 GP)

During a Short Rest, you can administer the Raw Honey Compress to yourself or another willing creature within 5 feet of yourself. If the creature spends Hit Point Dice during their Short Rest, they also regain 1d6 Hit Points.

Saltpeter Tonic (15 GP)

As a Bonus Action, you can drink a vial of Saltpeter Tonic to gain Advantage on their next saving throw against the Poisoned condition within 10 minutes.

Diseases. Suppresses Inflammation for 10 minutes.

Sanguine Tincture (50 GP)

As a Bonus Action, you can drink or administer the Sanguine Tincture to another creature within 5 feet of yourself. The creature that drinks the fluid in this vial gains 2d6 Temporary Points.

Spirit of Hartshorn (25 GP)

When inhaled, the drinker immediately awakens if unconscious and gains 10 feet of movement for 1 minute. The fumes are disorienting, causing Disadvantage on Dexterity (Sleight of Hand) checks and Intelligence checks for the duration.

Diseases. Suppresses 1 level of Exhaustion, Weakness, and Dizziness for duration.

Tincture of Quicksilver (300 GP)

This tonic is a stimulant and mental enhancer derived from purified mercury. When ingested, it sharpens cognition and increases energy but scatters focus and leads to exhaustion once the effects wear off.

For 4 hours, the user gains +2 to Intelligence, +10 ft movement speed, and Advantage on saving throws against the Charmed condition. However, they also have Disadvantage on Concentration checks and must spend movement each turn due to restless energy.

Diseases. Suppresses 1 level of Exhaustion and Weakness for duration.

After the effects wear off, the user experiences a crash for 2 hours, suffering Disadvantage on all Intelligence and Dexterity checks and saving throws. Taking another dose alleviates these effects.

Verdigris Salve (50 GP)

As a Utilize Action, you can administer the Verdigris Salve to yourself or another willing creature within 5 feet of yourself. For 1 hour, the creature has Advantage on Constitution saving throws against contracting diseases spread through blood or physical contact.

Diseases. Suppresses Bleeding and Inflammation for duration.

Vinegar of Four Thieves (250 GP)

As a Bonus Action, you can administer the Vinegar of Four Thieves to yourself or another willing creature within 5 feet of yourself. A creature subjected to Vinegar of Four Thieves makes a DC 15 Constitution save when ingested or has the symptoms of The Blight for 24 hours (Nausea, Vomiting, Diarrhea).

Diseases. A creature who fails their save is cured of any disease at the end of 24 hours. On a success, the concoction has no effect and any disease remains. Creatures who succeed on their save are immune to the effects of the concoction for 48 hours.